{"product_id":"l-pdrn-first™","title":"L-PDRN First™","description":"\u003cp\u003e\u003cstrong\u003eL-PDRN First™\u003c\/strong\u003e is a solution of low molecular weight, \u003cmeta charset=\"utf-8\"\u003evegan PDRN derived from \u003cem\u003eLactobacillus rhamnosus\u003c\/em\u003e fermentation that aids in the growth of new skin cells and barrier repair. These DNA fragments have been c\u003cspan\u003elinically shown to stimulate collagen-producing cells (\u003cmeta charset=\"utf-8\"\u003efibroblasts) and to boost tissue repair (Shin et al., 2023). PDRN is one of the most in-demand ingredients used in K-beauty formulations as it promotes the \"glass skin\" effect or a dewy appearance. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan data-cur=\"cursor\" data-contrast=\"auto\"\u003ePDRN activates A2A adenosine receptors, which regulate anti-inflammatory responses, promote cell growth and \u003c\/span\u003e\u003cspan data-cur=\"cursor\" data-contrast=\"auto\"\u003estimulate new blood vessel formation\u003c\/span\u003e\u003cspan data-cur=\"cursor\" data-contrast=\"auto\"\u003e. This improves oxygen and nutrient delivery to the skin, which is key for skin longevity. \u003cmeta charset=\"utf-8\"\u003e \u003cstrong\u003eL-PDRN First™\u003c\/strong\u003e has enhanced topical absorption \u003c\/span\u003e\u003c\/span\u003edue to its \u0026lt; 100bp size compared to salmon PDRN, which is typically 200-800bp. It is identical in performance to traditional PDRN in both safety and efficacy and considered an eco-friendly, sustainable alternative to salmon PDRN.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCosmetic Applications:\u003c\/strong\u003e \u003cbr\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003e• Wound healing and post-procedure repair\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• Barrier repair\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• Antioxidant (more than 2X SOD-like activity)\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• \u003cmeta charset=\"utf-8\"\u003eInflammation reduction\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis product should be added to a formulation at the recommended usage rate. Disclaimer Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cstrong\u003eINCI:\u003c\/strong\u003e Lactobacillus Ferment Lysate, Hydrolyzed DNA, Sodium DNA, 1,2- Hexanediol, Sodium Chloride, Ethylhexylglycerin\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCalifornia Prop 65 Statement:\u003c\/strong\u003e \u003c\/p\u003e\n\u003ch5\u003eSDS \u0026amp; Tech Data\u003c\/h5\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/files\/Specification_Sheet_-_L-PDRN_First.pdf?v=1776372846\" title=\"Specification Sheet - L-PDRN First™\" rel=\"noopener\" data-cur=\"pointer\" target=\"_blank\"\u003e\u003cspan data-cur=\"pointer\"\u003eL-PDRN First™\u003c\/span\u003e Specification Sheet\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/files\/sds_l-pdrn_first_20260416.pdf?v=1776372846\" title=\"SDS L-PDRN First™\" rel=\"noopener\" data-cur=\"pointer\" target=\"_blank\"\u003e\u003cspan data-cur=\"pointer\"\u003eL-PDRN First™\u003c\/span\u003e SDS\u003c\/a\u003e\u003c\/p\u003e\n\u003ch5\u003eFormulation Guide\u003c\/h5\u003e\n\u003cp\u003e\u003cstrong\u003eIncorporation:\u003c\/strong\u003e L-PDRN First™ should be incorporated into the water phase in a cold-process system. If hot-processing, add below 45°C, during the cooling phase after emulsification.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Use Level:\u003c\/strong\u003e  2%\u003cbr\u003e\u003cstrong\u003eHeat Sensitivity:\u003c\/strong\u003e Avoid prolonged exposure to high temperatures to maintain ingredient performance.\u003cbr\u003e\u003cstrong\u003epH Range:\u003c\/strong\u003e 4.0 – 8.0\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Water-soluble\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormulation types:\u003c\/strong\u003e Suitable for a wide range of skincare formulations, including serums, creams, toners, and gels\u003c\/p\u003e\n\u003cp\u003eTry out these formulations using this ingredient:\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Undisclosed","offers":[{"title":"8g (.25 oz) - $11.55","offer_id":42711752278112,"sku":"LPDRN-008","price":11.55,"currency_code":"USD","in_stock":true},{"title":"15g (0.52 oz) - $16.95","offer_id":42711752310880,"sku":"LPDRN-15","price":16.95,"currency_code":"USD","in_stock":true},{"title":"30g (1.05 oz) - $29.85","offer_id":42711752343648,"sku":"LPDRN-30","price":29.85,"currency_code":"USD","in_stock":true},{"title":"60g (2.11 oz) - $54.95","offer_id":42711752376416,"sku":"LPDRN-60","price":54.95,"currency_code":"USD","in_stock":true},{"title":"120g (4.23 oz) - $99.85","offer_id":42711752409184,"sku":"LPDRN-120","price":99.85,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/files\/polysorbate-20_1800x1800_1800x1800_6a0825a2-6adc-455d-9a77-d0f547115210.webp?v=1771366170","url":"https:\/\/lotioncrafter.com\/products\/l-pdrn-first%e2%84%a2","provider":"Lotioncrafter","version":"1.0","type":"link"}