Serilesine® Solution GC

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 **THIS IS A CLOSEOUT ITEM THAT WILL ONLY BE AVAILABLE AS SUPPLIES LAST. Our current lot has a retest date of 07/2021**

Serilesine® is a hexapeptide; a synthesized sequence from the alpha chain of Laminin. This peptide retains many of the chracteristics of the native protein, and promotes cell adhesion and proliferation. Certain features of the DEJ (the dermal epidermal junction) are altered by the aging process, such as the anchoring ability of keratinocytes, probably due to deficiencies in the expression of integrins as we age.

Laminin-5 synthesis has also been proved to decrease in aged skin. This causes a loss of contact between dermis and epidermis, and results in the skin losing elasticity and becoming saggy. The cohesion between dermis and epidermis is essential to maintain skin balance because it enables the transport of oxygen, nutrients and waste, contributing to the health of the epidermis. Serilesine's synthetic hexapeptide from Laminin-1 is able to restore the skin’s normal function by promoting synthesis of Laminin-5, stimulating keratinocyte and fibroblast proliferation, inducing a redensifying effect on the dermis, and an improvement in skin elasticity, compactness, tonicity and smoothness.

Serilesine® Solution GC can be incorporated in cosmetic formulations such as emulsions, gels, and serums where restructuring and refirming of skin is desired.


  • Improves cell adhesion by enhancing synthesis of laminin-5
  • Adhesion of cells to the basement membrane and among themselves provides firmness to the skin
  • Increased contact between skin cells ensures correct nourishment and health
  • Induces a significant increase in dermis density, improving skin compactness

Active Ingredient Content:  0.5% Hexapeptide-10

INCI: Water (and) Hexapeptide-10

Important Note:  Serilesine® is a trademark of Lipotec and it cannot be referenced in your marketing literature without a signed Trademark Agreement with Lipotec.

Do not directly apply onto your skin. This product should be added to a formulation at the recommended usage rate.

Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.

California Prop 65 Statement: The following statement is made in order to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects or other reproductive harm.

To request technical documentation, please contact Lotioncrafter at

Serilesine® Solution GCC can be incorporated at the final stage of the manufacturing process, provided the temperature is below 40°C (104°F). Taking into consideration the concentration of peptide in Serilesine® Solution GC, it is recommended that 1 - 10% of the solution be present in the final formulation in order to obtain significant restructuring activity. 

Recommended Usage Rate: 1-10%
Appearance: Colorless, translucent solution
pH of Raw Material: 3.0 - 6.0
Solubility: Water soluble
Raw Material Preserved With: Glycerin and Caprylyl Glycol
Long Term Storage:  Cool, clean and dark place. If kept in these conditions shelf life is at least 24 months.


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