Tetrapeptide-3 Solution

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Tetrapeptide-3 Solution™ is a biomimetic lipopeptide derived from a growth factor that boosts the production of key components at the dermoepidermal junction (DEJ) for maximal reduction in the appearance of fine lines and wrinkles.

The DEJ maintains skin cohesion and supports skin metabolic needs for a young and healthy look. As we age, at the cellular level, we experience a decrease in epidermal thickness, combined with a flattening of the dermoepidermal junction (DEJ) which decreases the amount of nutrients available to the epidermis thus interfering with the skin's natural repair process.  This leads to a loss of elasticity, support and firmness, skin fragility and the appearance of fine lines and wrinkles.

The major components of the DEJ are:

  • Laminin-5: Anchors the epidermis to the dermis for structural support
  • Collagen VII: Anchors the dermis to the DEJ for mechanical stability
  • Fibronectin: Anchors cells to the extracellular matrix (ECM) for cell adhesion

Tetrapeptide-3 Solution™ stimulates production of Collagen VII, laminin-5, and fibronectin at the DEJ and activates natural skin repair.


  • Wrinkle reduction
  • Skin rejuvenation
  • Evenness of skin texture
  • Firmer and smoother skin
  • Younger look


  • Anti-aging care
  • Skin repair treatment
  • Mature skin care
  • Specific care (eye, lips, etc)
  • Men care
  • Stretch marks
  • Dermocosmetic care (in combination with corticoids)
  • Alternative to cosmetic surgery

INCI: Glycerin, Water, Dextran, Caprooyl Tetrapeptide-3

Do not directly apply onto your skin. This product should be added to a formulation at the recommended usage rate.

Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.

California Prop 65 Statement: The following statement is made in order to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects or other reproductive harm.

Tetrapeptide-3 Solution Specification Sheet

Tetrapeptide-3 Solution SDS - Coming Soon!

Incorporation: Add at the end of the manufacturing process, at or below 40°C (104°F).
Usage pH Range: 5.3 - 7.3
Recommended Usage Rate: 0.3 - 2.5%

  • Intensive treatment: 2.5%
  • Preventive treatment: 1 - 2.5%
  • Skin repair treatment: 0.3 - 1%

Appearance: Transparent aqueous liquid, odorless
Solubility: Water soluble
Preservative: None
Long-Term Storage: Room Temperature
Shelf-Life: 3 years from the date of manufacture

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