Tripeptide-2 Solution

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Tripeptide-2 Solution is a 3 amino acid peptide biomimetic of Elafin, an enzyme inhibitor involved in extracellular matrix integrity. 

Progerin is a senescence marker discovered through the understanding of Progeria, an accelerated aging condition in children.  Senescence is characterized by a build-up of progerin, a toxic protein which is critical for cellular activity (nucleus structure and DNA replication).  The accumulation of progerin causes nuclear defects and DNA damage, thus contributing to the appearance of signs of aging.

Present in fibroblasts and keratinocyes, progerin accumulates with time with higher levels occurring later in life.  Progerin expression is now used as a biomarker of cellular aging.

Tripeptide-2 Solution decreases progerin synthesis by acting directly on the senescence process to improve the signs associated with skin maturation: sagging, slacking and wrinkles.


  • Anti-aging care
  • Mature skin care
  • Firming Care
  • Remodeling skin care
  • Post-pregnancy care
  • Body care
  • Men care
  • Photoaging
  • Alternative to cosmetic surgery

INCI: Glycerin, Water, Dextran, Trifluoroacetyl Tripeptide-2

Do not directly apply onto your skin. This product should be added to a formulation at the recommended usage rate.

Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.

California Prop 65 Statement: The following statement is made in order to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects or other reproductive harm.

Tripeptide-2 Solution Specification Sheet - Coming Soon!

Tripeptide-2 Solution SDS - Coming Soon!

  • Due to the chemical nature of Tripeptide-2 Solution, it is recommended to avoid combination with sugars to prevent any possible Maillard reaction (browning of the formulation).
  • At pH greater that 5.5, there is a risk of degradation of the peptide.
  • Add at the end of the manufacturing process, at or below 40°C (104°F).

    Recommended Usage Rate: 0.5 - 2.0%
    Recommended pH Range: 4.0 - 5.5
    Appearance: Clear, aqueous liquid, odorless
    Solubility: Water soluble
    Preservative: None

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